Cyproterone acetate as initial treatment and maintenance therapy for hirsutism.

@article{Holdaway1985CyproteroneAA,
  title={Cyproterone acetate as initial treatment and maintenance therapy for hirsutism.},
  author={I. Holdaway and M. Croxson and H. Ibbertson and A. Sheehan and B. Knox and J. France},
  journal={Acta endocrinologica},
  year={1985},
  volume={109 4},
  pages={
          522-9
        }
}
Thirty-four patients with hirsutism were treated for 9 months with 100 mg cyproterone acetate (CA) given on days 5-15 of the menstrual cycle together with a combination oral contraceptive containing 2 mg CA and 50 micrograms ethinyloestradiol (Diane) given on days 5-25 of the cycle. After 9 months treatment patients were randomised to a 12 month double-blind cross-over trial comparing Diane plus 25 mg CA with Diane plus placebo, to test the efficacy of low-dose CA as maintenance therapy. Thirty… Expand
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