Cyproteronacetate in the management of severe acne in males

  title={Cyproteronacetate in the management of severe acne in males},
  author={R. Cormane and H. V. D. Meeren},
  journal={Archives of Dermatological Research},
SummaryWe report the results of an investigation of the antiandrogen cyproteronacetate (Androcur) in the management of acne vulgaris in the male patient. The interim report covers our experiences with 11 patients treated with an orally administered dose of 25 mg cyproteronacetate. Marked improvement was noticed in most instances. Side effects were minimal. This study shows that cyproteronacetate is an effective agent in the control of recalcitrant acne in males.ZusammenfassungWir berichten über… Expand
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Acne: double blind clinical and laboratory trial of tetracycline, oestrogen-cyproterone acetate, and combined treatment.
Adding antibiotics offers no advantage over using oestrogen-cyproterone on its own, although in this study the combination was more effective than tetracycline alone at six months. Expand
Chapter 19. Pharmacological Developments in Dermatology
This chapter includes specific developments made concerning psoriasis, atopic dermatitis, acne, and more general sections on inflammatory mediators likely to play a role in skin inflammation, topical anti-inflammatories, and vehicles of current use in topical therapy. Expand


Antiandrogens in the treatment of sexual deviations of men.
Cyproterone acetate therapy has proved itself to be a valuable aid in psychotherapy of sexual deviations and perversions in that the perverse cycle is interrupted and a “sexual calm” is created as a starting point for psychotherapy. Expand
Reduction of sebum excretion in man by the antiandrogen, cyproterone acetate
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The role of antiandrogenic action in cyproterone acetate-induced morphologic and biochemical changes in human semen.
The results indicate that the effects of a low dose of cyproterone acetate are due mainly to peripheral androgen deprivation. Expand
The effect of topically applied progesterone on sebum excretion rate
A signiticant reduction in sebum excretion rate was found in females and a significant loss of effect at the end of the third month was not related to deterioration of the progesterone preparation. Expand
The effects of low doses of cyproterone acetate on some functions of the reproductive system in normal men.
The results indicate that daily doses of 5 mg and 10 mg of cyproterone acetate are not effective as a male contraceptive. Expand
Pharmacology and potential use of cyproterone acetate.
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[Modification of fertility of the male by antiandrogens].
Current studies do not allow a conclusive evaluation of the applicability of CPA for fertility control in men, and a distinct modification of spermatogenesis and posttesticular sperm maturation processes cannot be demonstrated in the dosage range studied. Expand
Classification of Acne Vulgaris
The lack of an internationally accepted scheme for classifying and grading the severity of acne has been a prime source of confusion and controversy and hampers every field of investigation beginning with epidemiologic surveys concerning the prevalence of acne in different countries. Expand
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An interdisciplinary group interested in cutaneous biology has met to discuss varying topic topics at Brown University and at the Oregon Regional Primate Research Center. Expand
Beeinflussung der Fertilit~it des Mannes dutch Antiandrogene
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  • 1980