Cypermethrin increases apo A-1 and apo B mRNA but not hyperlipidemia in rats.

  title={Cypermethrin increases apo A-1 and apo B mRNA but not hyperlipidemia in rats.},
  author={L Aldana and Elvira Gonzalez de Mejia and Arthur L. Craigmill and V{\'i}ctor Tsutsumi and Juan Armend{\'a}riz-Borunda and Arturo Panduro and Ana Rosa Rinc{\'o}n},
  journal={Toxicology letters},
  volume={95 1},
The hepatotoxic effect of cypermethrin and the expression of hepatic genes at the mRNA level, as molecular markers of liver damage, were evaluated in rats following exposure to cypermethrin. The expression of hepatic genes was compared with conventional liver functional tests, and correlations were made by studying the liver at the ultrastructural level. Cypermethrin treated rats presented a significant decrease, of 79% and 22%, on the expression of albumin and apo E genes at 5 days… CONTINUE READING
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