Cypermethrin has the potential to induce hepatic oxidative stress, DNA damage and apoptosis in adult zebrafish (Danio rerio).

@article{Jin2011CypermethrinHT,
  title={Cypermethrin has the potential to induce hepatic oxidative stress, DNA damage and apoptosis in adult zebrafish (Danio rerio).},
  author={Yuanxiang Jin and Shanshan Zheng and Yue Pu and Linjun Shu and Liwei Sun and Wei-Ping Liu and Zhengwei Fu},
  journal={Chemosphere},
  year={2011},
  volume={82 3},
  pages={398-404}
}
Cypermethrin (CYP), a widely used Type II pyrethroid pesticide, is one of the most common contaminants in the freshwater aquatic system. We studied the effects of CYP exposure on the induction of hepatic oxidative stress, DNA damage and the alteration of gene expression related to apoptosis in adult zebrafish. Hepatic mRNA levels for the genes encoding antioxidant proteins, such as Cu/Zn-Sod, Mn-Sod, Cat, and Gpx, were significantly upregulated when zebrafish were exposed to various… CONTINUE READING