Cylindrene, a novel sesquiterpenoid from Imperata cylindrica with inhibitory activity on contractions of vascular smooth muscle.

  title={Cylindrene, a novel sesquiterpenoid from Imperata cylindrica with inhibitory activity on contractions of vascular smooth muscle.},
  author={Kimihiro Matsunaga and Masao Shibuya and Yasushi Ohizumi},
  journal={Journal of natural products},
  volume={57 8},
CD24 gene inhibition and TIMP-4 gene upregulation by Imperata cylindrica's root extract prevents metastasis of CaSki cells via inhibiting PI3K/Akt/snail signaling pathway and blocking EMT.
Findings provide an anti-metastatic mechanism of action of I. cylindrica root extract toward the human cervical cancer suggesting that this plant maybe developed into selective chemotherapy.
A botanical from the antiproliferative Cameroonian spice, Imperata cylindrica is safe at lower doses, as demonstrated by oral acute and sub-chronic toxicity screenings
Oral sub-chronic exposure of ICR at lower doses are recommended while higher doses around 1000 mg/kg b.w. should be discouraged, however, for long-term oral administration, safety measures should be taken.
Halophytic Grasses, a New Source of Nutraceuticals? A Review on Their Secondary Metabolites and Biological Activities
The Poaceae family, known as grasses, is distributed worldwide and is considered the most important group of monocotyledonous crops. Salt stress is multifactorial, therefore to survive, halophytes
Three novel 14-epiarborane triterpenoids from Imperata cylindrica Beauv. var. major
Abstract Three novel triterpenoids, 14-epiarbor-7-en-3β-ol (1), 14-epiarbor-7-en-3β-yl formate (2) and 14-epiarbor-7-en-3-one (3) were isolated from the rhizomes of Imperata cylindrica. Their
Isoeugenin, a Novel Nitric Oxide Synthase Inhibitor Isolated from the Rhizomes of Imperata cylindrica
The results suggest that the new chromone isoegenin should be considered a potential treatment for inflammatory disease.
Phosphoproteomic profiling of microsomal fractions in leaves of Cogon grass ('Imperata cylindrica')
The phosphoproteomic study identified differentially phosphorylated peptides of membrane proteins which may play an important role in the salt stress response of 'Imperata'.
Tabanone, a New Phytotoxic Constituent of Cogongrass (Imperata cylindrica)
Bioactivity-guided fractionation of this extract using silica gel column chromatography led to the identification of megastigmatrienone, 4-(2-butenylidene)-3,5,5-trimethyl-2-cyclohexen-1-one (also called tabanone), as a mixture of four stereoisomers responsible for most of the activity.
Chemical Composition and Hepato-protective activity of Imperata cylindrica Beauv
Phytochemical study of the aerial parts of Imperata cylindrica Beauv. (Graminae), growing in Egypt afforded four methoxylated flavonoids 1-4 , β-sitosterol-3-0-β-D-glucopyranosyl-6 ' -tetradecanoate
A new lignan glycoside from the rhizomes of Imperata cylindrica
A new lignan glycoside, 6-acetyl-1-[1,3-(4,4′-dihydroxy-3,3′-dimethoxy-β-truxinyl)-β-d-fructofuranosyl]-α-d-glucopyranoside (1), named impecyloside, was isolated from the rhizomes of Imperata
Ecotypic variation of a medicinal plant Imperata cylindrica populations in Taiwan: mass spectrometry-based proteomic evidence
Proteomic results provide additional evidence of the ecotypic variation among Imperata cylindrica ecotypes and the potential use of this novel approach to identify protein markers is discussed in the study.