Cyclotide synthesis and supply: from plant to bioprocess.

@article{Drnenburg2010CyclotideSA,
  title={Cyclotide synthesis and supply: from plant to bioprocess.},
  author={Heike D{\"o}rnenburg},
  journal={Biopolymers},
  year={2010},
  volume={94 5},
  pages={602-10}
}
Cyclotides are disulfide-rich miniproteins with a circular backbone and a knotted arrangement ofdisulfide bonds. Because these plant-derived peptides are resistant to degradation and exhibit a diverse range of bioactivity they have become important agronomic and industrial objectives. They belong to a group of compounds with low market volume and high price that are poorly processed by microorganisms, are too complex for economic chemical synthesis, and thus are valuable candidates for the… CONTINUE READING

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