Cyclosporine monitoring with 2-hour postdose levels in heart transplant recipients.

@article{Solari2005CyclosporineMW,
  title={Cyclosporine monitoring with 2-hour postdose levels in heart transplant recipients.},
  author={Sandra G Solari and Lee R. Goldberg and David Denofrio and Leslie M. Shaw},
  journal={Therapeutic drug monitoring},
  year={2005},
  volume={27 4},
  pages={417-21}
}
Cyclosporine therapeutic drug monitoring based on 2-hour postdose concentration (C2) compared with conventional trough concentration (C0) can improve clinical outcomes for de novo renal and liver transplant patients. However, in heart transplant patients, published studies are limited. To determine the clinical significance of C2 compared with C0 following orthotopic heart transplantation, the authors measured CsA at C0 and C2 and estimated CsA area under the curve (AUC) using Bayesian… CONTINUE READING

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