Cyclosporine-induced stimulation of the renin-angiotensin system after liver and heart transplantation.

@article{Julien1993CyclosporineinducedSO,
  title={Cyclosporine-induced stimulation of the renin-angiotensin system after liver and heart transplantation.},
  author={Jean-Pierre Julien and Dominique Farge and Carmen Kreft-Jais and Than Tam Guyene and Pierre-François Plouin and Didier P Houssin and Andr{\'e} Carpentier and Pierre Corvol},
  journal={Transplantation},
  year={1993},
  volume={56 4},
  pages={885-91}
}
To analyze the status of the renin-angiotensin system in hypertensive transplant recipients on cyclosporine, we prospectively explored 21 cardiac (CTR: 52 +/- 8.2 yr) and 12 liver (LTR: 45 +/- 10 yr) transplant recipients on a normal salt diet with 19 normotensive controls in the same age range. Systolic and diastolic blood pressure was measured in the supine and standing positions. Renal function was assessed by serum creatinine values, and 24-hr urinary sodium and potassium excretion were… CONTINUE READING
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