Cyclosporine and tacrolimus for the treatment of rheumatoid arthritis.

@article{Kitahara2007CyclosporineAT,
  title={Cyclosporine and tacrolimus for the treatment of rheumatoid arthritis.},
  author={Kanako Kitahara and Shinichi Kawai},
  journal={Current opinion in rheumatology},
  year={2007},
  volume={19 3},
  pages={238-45}
}
PURPOSE OF REVIEW The calcineurin inhibitors cyclosporine and tacrolimus are important treatments for patients with active rheumatoid arthritis, especially in cases of resistance or intolerance to methotrexate or other disease-modifying antirheumatic drugs. Here, we discuss the mechanism, efficacy and safety of cyclosporine and tacrolimus in the treatment of rheumatoid arthritis. RECENT FINDINGS Recent clinical trials of cyclosporine have shown the advantages of its combination with… CONTINUE READING

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