Cyclosporine A or intravenous cyclophosphamide for lupus nephritis: the Cyclofa-Lune study.

@article{Zavada2010CyclosporineAO,
  title={Cyclosporine A or intravenous cyclophosphamide for lupus nephritis: the Cyclofa-Lune study.},
  author={Jakub Zavada and Ss Pesickova and Romana Ry{\vs}av{\'a} and Marta Olej{\'a}rov{\'a} and Peter Horak and Zbyněk Hrn{\vc}{\'i}ř and Ivan Rychlik and Martin Havrda and J V{\'i}tov{\'a} and Jozef Luk{\'a}{\vc} and Josef Rovensky and Dana Tegzov{\'a} and Jana B{\"o}hmov{\'a} and Josef Zadra{\vz}il and Jiamao Hana and Ctibor Dostal and Vladim{\'i}r Tesař},
  journal={Lupus},
  year={2010},
  volume={19 11},
  pages={1281-9}
}
Intravenous cyclophosphamide is considered to be the standard of care for the treatment of proliferative lupus nephritis. However, its use is limited by potentially severe toxic effects. Cyclosporine A has been suggested to be an efficient and safe treatment alternative to cyclophosphamide. Forty patients with clinically active proliferative lupus nephritis were randomly assigned to one of two sequential induction and maintenance treatment regimens based either on cyclophosphamide or… CONTINUE READING
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