Cyclosporine A mediates fibroproliferation through epithelial cells.


BACKGROUND Obliterative bronchiolitis (OB) is the major cause of morbidity and mortality after lung transplantation. The potential role of immunosuppressive drugs in the development of OB is uncertain, but there are limited data indicating that cyclosporine A (CsA) may have a direct fibrogenic effect on various human cell types. Epithelium-fibroblast… (More)


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@article{Hostettler2004CyclosporineAM, title={Cyclosporine A mediates fibroproliferation through epithelial cells.}, author={Katrin E. Hostettler and Michael Roth and Janette K Burgess and Peter A. Johnson and Allan R Glanville and Michael Tamm and Judith Lee Black and Peter Borger}, journal={Transplantation}, year={2004}, volume={77 12}, pages={1886-93} }