Cyclosporin treatment for rheumatoid arthritis: a placebo controlled, double blind, multicentre study.

@article{Rijthoven1986CyclosporinTF,
  title={Cyclosporin treatment for rheumatoid arthritis: a placebo controlled, double blind, multicentre study.},
  author={Andre W A M van Rijthoven and Ben A. C. Dijkmans and H S Goei Th{\'e} and J E Hermans and Z. L. B. M. Montnor-Beckers and P. C. J. Jacobs and Arnold Cats},
  journal={Annals of the rheumatic diseases},
  year={1986},
  volume={45 9},
  pages={726-31}
}
The efficacy and safety of cyclosporin for patients with rheumatoid arthritis (RA) were assessed in a six month double blind, placebo controlled, multicentre study. The initial dosage of the drug was 10 mg/kg daily for two months. There were many discontinuations in both the cyclosporin group (eight out of 17) and the placebo group (six out of 19). Of the patients who completed the six months of therapy, those who had received cyclosporin showed a significant improvement in the number of… CONTINUE READING