Cyclosporin A is superior to cyclophosphamide in children with steroid-resistant nephrotic syndrome—a randomized controlled multicentre trial by the Arbeitsgemeinschaft für Pädiatrische Nephrologie

@article{Plank2008CyclosporinAI,
  title={Cyclosporin A is superior to cyclophosphamide in children with steroid-resistant nephrotic syndrome—a randomized controlled multicentre trial by the Arbeitsgemeinschaft f{\"u}r P{\"a}diatrische Nephrologie},
  author={Christian Plank and Veronica Kalb and Bernward Hinkes and Friedhelm Hildebrandt and Olaf Gefeller and Wolfgang Rascher and for Arbeitsgemeinschaft f{\"u}r P{\"a}diatrische Nephrologie},
  journal={Pediatric Nephrology},
  year={2008},
  volume={23},
  pages={1483-1493}
}
  • Christian Plank, Veronica Kalb, +4 authors for Arbeitsgemeinschaft für Pädiatrische Nephrologie
  • Published in Pediatric Nephrology 2008
  • DOI:10.1007/s00467-008-0794-1
First line immunosuppressive treatment in steroid-resistant nephrotic syndrome in children is still open to discussion. We conducted a controlled multicentre randomized open label trial to test the efficacy and safety of cyclosporin A (CSA) versus cyclophosphamide pulses (CPH) in the initial therapy of children with newly diagnosed primary steroid-resistant nephrotic syndrome and histologically proven minimal change disease, focal segmental glomerulosclerosis or mesangial hypercellularity… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 59 CITATIONS, ESTIMATED 53% COVERAGE

Cyclophosphamide versus cyclosporine A therapy in steroid-resistant nephrotic syndrome: a retrospective study with a mean 5-year follow-up

  • The Journal of international medical research
  • 2018
VIEW 9 EXCERPTS
CITES BACKGROUND & RESULTS
HIGHLY INFLUENCED

Tacrolimus as rescue therapy for adult-onset refractory minimal change nephrotic syndrome with reversible acute renal failure.

  • Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
  • 2013
VIEW 6 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Therapies for steroid-resistant nephrotic syndrome

  • Pediatric Nephrology
  • 2008
VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Immunosuppression and renal outcome in congenital and pediatric steroid-resistant nephrotic syndrome.

  • Clinical journal of the American Society of Nephrology : CJASN
  • 2010
VIEW 4 EXCERPTS
CITES BACKGROUND & RESULTS
HIGHLY INFLUENCED

Nephrotisches Syndrom des Kindes- und Jugendalters

R. Ehren, P. Brinkkötter, L. T. Weber, U. Querfeld
  • Der Nephrologe
  • 2019
VIEW 1 EXCERPT
CITES BACKGROUND

FILTER CITATIONS BY YEAR

2008
2019

CITATION STATISTICS

  • 5 Highly Influenced Citations

References

Publications referenced by this paper.
SHOWING 1-10 OF 43 REFERENCES

High-dose oral cyclosporin therapy for recurrent focal segmental glomerulosclerosis in children.

  • American journal of kidney diseases : the official journal of the National Kidney Foundation
  • 2004
VIEW 11 EXCERPTS
HIGHLY INFLUENTIAL

Interventions for idiopathic steroid-resistant nephrotic syndrome in children.

  • The Cochrane database of systematic reviews
  • 2004
VIEW 3 EXCERPTS
HIGHLY INFLUENTIAL

Mutations in the Wilms ’ tumor 1 gene cause isolated steroid resistant nephrotic syndrome and occur in exons 8 and 9

C Ponticelli, G Rizzoni, +10 authors O DellaCasa-Alberighi
  • Pediatr Res
  • 2006

Long-term effects of cyclosporine in children with idiopathic nephrotic syndrome: a single-centre experience.

  • Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
  • 2005

Single-centre experience with cyclosporin in 106 children with idiopathic focal segmental glomerulosclerosis.

  • Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
  • 2005

Efficacy of IV pulse cyclophosphamide (CP) vs iv steroids & oral CP for steroid resistant nephrotic syndrome

M Mantan, A Bagga, C Siriam, P Hari
  • Pediatr Nephrol 19:C73
  • 2004
VIEW 2 EXCERPTS