Cyclosporin A in the treatment of acute exacerbation of idiopathic pulmonary fibrosis.

@article{Sakamoto2010CyclosporinAI,
  title={Cyclosporin A in the treatment of acute exacerbation of idiopathic pulmonary fibrosis.},
  author={Susumu Sakamoto and Sakae Homma and Atsushi Miyamoto and Atsuko Kurosaki and Takeshi Fujii and Kunihiko Yoshimura},
  journal={Internal medicine},
  year={2010},
  volume={49 2},
  pages={
          109-15
        }
}
BACKGROUND Acute exacerbation (AE) of idiopathic pulmonary fibrosis (IPF) is considered to be a nearly fatal condition during the clinical course of IPF, as it is unresponsive to most conventional therapies. SUBJECTS AND METHODS To evaluate the efficacy of cyclosporin A (CsA) for AE of IPF, we conducted a retrospective study on autopsied IPF cases who developed AE and were treated with corticosteroids (CS) combined with CsA. The subjects comprised 11 males with a mean age of 69.9 years. The… CONTINUE READING

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