Cyclosporin A does not modify Langerhans' cell number and distribution in normal human skin.

@article{Urabe1989CyclosporinAD,
  title={Cyclosporin A does not modify Langerhans' cell number and distribution in normal human skin.},
  author={Atsushi Urabe and Marek Haftek and Jean Kanitakis and Daniel R Schmitt and Jean Thivolet},
  journal={Acta dermato-venereologica},
  year={1989},
  volume={69 3},
  pages={249-52}
}
We used the model of human skin graft on nude mouse to investigate a possible influence of systemically administered cyclosporin A (CsA) on epidermal Langerhans' cells (LC). This experimental model has the advantage of being independent of the systemic humoral and cellular influences of a human host. No change in the human LC distribution or number could be… CONTINUE READING