Cyclophosphamide therapy in pediatric multiple sclerosis.

  title={Cyclophosphamide therapy in pediatric multiple sclerosis.},
  author={Naila Makhani and Mark P. Gorman and Helen M. Branson and Lynn Stazzone and Brenda L. Banwell and Tanuja Chitnis},
  volume={72 24},
OBJECTIVE To review our multicenter experience with cyclophosphamide in the treatment of children with multiple sclerosis (MS). METHODS Retrospective chart review of children with MS treated with cyclophosphamide. Demographic, clinical, treatment, and MRI parameters were collected. RESULTS We identified 17 children with MS treated with cyclophosphamide. All but one had worsening of Expanded Disability Status Scale scores or multiple relapses prior to treatment initiation. Children were… CONTINUE READING