Cyclophosphamide-induced cytogenetic effects in mouse bone marrow and spleen cells in in vivo and in vivo/in vitro assays.

@article{Krishna1987CyclophosphamideinducedCE,
  title={Cyclophosphamide-induced cytogenetic effects in mouse bone marrow and spleen cells in in vivo and in vivo/in vitro assays.},
  author={G. R. Aditya Krishna and Joginder Nath and Morten Petersen and Tong-man Ong},
  journal={Teratogenesis, carcinogenesis, and mutagenesis},
  year={1987},
  volume={7 2},
  pages={183-95}
}
Sister chromatid exchange (SCE) and chromosomal aberration studies have been used to monitor human populations for genotoxic exposure to chemical substances. These monitoring techniques involve collection of blood and/or bone marrow from the exposed subjects and culturing cells for one or two cell cycles with various treatments in culture. The results… CONTINUE READING