Cyclophosphamide cardiotoxicity

  title={Cyclophosphamide cardiotoxicity},
  author={G. von Bernuth and Dieter Adam and Roland Hofstetter and Dieter Lang and Winfried Mohr and Elisabeth Kohne and Dietrich Niethammer},
  journal={European Journal of Pediatrics},
A 12-year-old boy with aplastic anemia developed severe but reversible cardiac failure after treatment with 200 mg/kg cyclophosphamide (4×50 mg/kg on four consecutive days) given as preparation for bone marrow grafting. This and previously reported cases demonstrate the possibility of cardiotoxicity after high doses of the drug. 

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Highdose cyclophosphamide therapy for malignant disease

  • C. D. Buckner, R. H. Rudolph, +7 authors E. D. Thomas
  • Cancer 29, 357--365
  • 1972
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