Cyclophilin Inhibitors as a Novel HCV Therapy

Abstract

A critical role of Cyclophilins, mostly Cyclophilin A (CyPA), in the replication of HCV is supported by a growing body of in vitro and in vivo evidence. CyPA probably interacts directly with nonstructural protein 5A to exert its effect, through its peptidyl-prolyl isomerase activity, on maintaining the proper structure and function of the HCV replicase. The… (More)
DOI: 10.3390/v2081621

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Cite this paper

@inproceedings{Tang2010CyclophilinIA, title={Cyclophilin Inhibitors as a Novel HCV Therapy}, author={Hengli Tang}, booktitle={Viruses}, year={2010} }