Cyclophilin B stimulates RNA synthesis by the HCV RNA dependent RNA polymerase.

Abstract

Cyclophilins are cellular peptidyl isomerases that have been implicated in regulating hepatitis C virus (HCV) replication. Cyclophilin B (CypB) is a target of cyclosporin A (CsA), an immunosuppressive drug recently shown to suppress HCV replication in cell culture. Watashi et al. recently demonstrated that CypB is important for efficient HCV replication… (More)
DOI: 10.1016/j.bcp.2008.12.019

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@article{Heck2009CyclophilinBS, title={Cyclophilin B stimulates RNA synthesis by the HCV RNA dependent RNA polymerase.}, author={Julie Akiko Heck and Xiao Meng and David N. Frick}, journal={Biochemical pharmacology}, year={2009}, volume={77 7}, pages={1173-80} }