Cyclooxygenases and lipoxygenases in cancer

  title={Cyclooxygenases and lipoxygenases in cancer},
  author={Claus Peter Schneider and Ambra Pozzi},
  journal={Cancer and Metastasis Reviews},
Cancer initiation and progression are multistep events that require cell proliferation, migration, extravasation to the blood or lymphatic vessels, arrest to the metastatic site, and ultimately secondary growth. Tumor cell functions at both primary or secondary sites are controlled by many different factors, including growth factors and their receptors, chemokines, nuclear receptors, cell–cell interactions, cell–matrix interactions, as well as oxygenated metabolites of arachidonic acid. The… CONTINUE READING
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