Cyclooxygenase inhibitors modulate NK activities that control metastatic disease

Abstract

Cyclooxygenase (COX) inhibitors have demonstrated efficacy in models of human cancer but the relevant mechanisms have not all been elucidated. Both Cox-dependent as well as Cox-independent mechanisms have been implicated. Using a syngeneic model of metastatic breast cancer, we have investigated the effect of Cox inhibitors on NK functions that are critical… (More)
DOI: 10.1007/s00262-005-0669-2

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@article{Kundu2005CyclooxygenaseIM, title={Cyclooxygenase inhibitors modulate NK activities that control metastatic disease}, author={Namita Kundu and Tonya C. Walser and Xinrong Ma and Amy M. Fulton}, journal={Cancer Immunology, Immunotherapy}, year={2005}, volume={54}, pages={981-987} }