Cyclooxygenase in biology and disease

@article{DuBois1998CyclooxygenaseIB,
  title={Cyclooxygenase in biology and disease},
  author={Raymond N DuBois and Steven B. Abramson and L. Crofford and R. Gupta and Lee S. Simon and Leo B. A. Putte and Peter E. Lipsky},
  journal={The FASEB Journal},
  year={1998},
  volume={12},
  pages={1063 - 1073}
}
  • Raymond N DuBois, Steven B. Abramson, +4 authors Peter E. Lipsky
  • Published 1998
  • Biology, Medicine
  • The FASEB Journal
  • Cyclooxygenase (COX), the key enzyme required for the conversion of arachidonic acid to prostaglandins was first identified over 20 years ago. Drugs, like aspirin, that inhibit cyclooxygenase activity have been available to the public for about 100 years. In the past decade, however, more progress has been made in understanding the role of cyclooxygenase enzymes in biology and disease than at any other time in history. Two cyclooxygenase isoforms have been identified and are referred to as COX… CONTINUE READING
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