Cyclooxygenase-2 is expressed in bladder during fetal development and stimulated by outlet obstruction.

@article{Park1997Cyclooxygenase2IE,
  title={Cyclooxygenase-2 is expressed in bladder during fetal development and stimulated by outlet obstruction.},
  author={John M. Park and Tianxin Yang and Lois J. Arend and Ann M Smart and J{\"u}rgen B. Schnermann and Josephine P. Briggs},
  journal={American journal of physiology. Renal physiology},
  year={1997},
  volume={273 4},
  pages={F538-F544}
}
Studies were undertaken to assess expression of inducible cyclooxygenase (COX)-2 in bladder during fetal development and COX-1 and COX-2 expression after outlet obstruction. Bladder tissue or bladder progenitor tissue was harvested from CD-1 murine embryos at embryonic days 11.5( E11.5), E14.5, E17.5, E20.5 (newborn), and from adult. Bladder obstruction was created in adult female mice by ligating the urethra, and bladders were harvested after 3-24 h of obstruction. Gene expression was assessed… CONTINUE READING

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