Cyclooxygenase-2 in normal, hyperplastic and neoplastic follicular cells of the human thyroid gland

@article{GarcaGonzlez2005Cyclooxygenase2IN,
  title={Cyclooxygenase-2 in normal, hyperplastic and neoplastic follicular cells of the human thyroid gland},
  author={Miguel Angel Garc{\'i}a-Gonz{\'a}lez and Ihab Abdulkader and Angel V{\'a}zquez Boquete and Xos{\'e} Manuel Lens Neo and Jer{\'o}nimo Forteza and Jos{\'e} Manuel Cameselle-Teijeiro},
  journal={Virchows Archiv},
  year={2005},
  volume={447},
  pages={12-17}
}
This study was undertaken to investigate cyclooxygenase-2 (COX-2) expression in follicular cells of the human thyroid. COX-2 expression was studied immunohistochemically in a total of 174 samples. COX-2 immunoreactivity was confined to the cell cytoplasm with the nuclei remaining unlabelled. COX-2 expression was observed in five cases (17.2%) of normal follicular cells and in one case (16.6%) of solid cell nests. Follicular carcinoma expressed COX-2 more frequently than follicular adenoma (93.4… CONTINUE READING

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