Cyclooxygenase-2 expression and angiogenesis in squamous cell carcinoma of the skin and its precursors: a paired immunohistochemical study of 35 cases.

@article{Nijsten2004Cyclooxygenase2EA,
  title={Cyclooxygenase-2 expression and angiogenesis in squamous cell carcinoma of the skin and its precursors: a paired immunohistochemical study of 35 cases.},
  author={T Nijsten and Cecile G A Colpaert and Peter B. Vermeulen and Al Harris and Eric van Marck and Julien Lambert},
  journal={The British journal of dermatology},
  year={2004},
  volume={151 4},
  pages={837-45}
}
BACKGROUND Cyclooxygenase (COX)-2 expression and tumour-induced angiogenesis appear to be increased in squamous cell carcinoma (SCC) of the skin. In other cancers, COX-2 is a pro-angiogenic factor. The association between angiogenesis and COX-2 has not been studied in skin cancer. OBJECTIVES To assess the onset of increased COX-2 expression and… CONTINUE READING