Cyclooxygenase-2 expression: a potential prognostic and predictive marker for high-grade ductal carcinoma in situ of the breast.

@article{Tan2004Cyclooxygenase2EA,
  title={Cyclooxygenase-2 expression: a potential prognostic and predictive marker for high-grade ductal carcinoma in situ of the breast.},
  author={Kong Bing Tan and W-P Yong and Thomas C. Putti},
  journal={Histopathology},
  year={2004},
  volume={44 1},
  pages={24-8}
}
AIMS To study cyclooxygenase-2 (COX-2) expression in ductal carcinoma in situ (DCIS) of the breast and its association with histological features. COX-2, an inducible prostaglandin synthase, has been shown to be important in mammary carcinogenesis, being associated with increased tumour size and unfavourable outcome in breast cancer. Animal studies indicate… CONTINUE READING