Cyclooxygenase-2 and c-erbB-2 expression in uterine cervical neoplasm assessed using tissue microarrays.

@article{Kim2005Cyclooxygenase2AC,
  title={Cyclooxygenase-2 and c-erbB-2 expression in uterine cervical neoplasm assessed using tissue microarrays.},
  author={Jung-Yeon Kim and Sung Jig Lim and Kyeongmee Park and Chul-Min Lee and Juree Kim},
  journal={Gynecologic oncology},
  year={2005},
  volume={97 2},
  pages={337-41}
}
OBJECTIVES Cyclooxygenase-2 (COX-2) and c-erbB-2 are involved in the pathogenesis of solid organ tumors. Chemotherapeutic agents targeting COX-2 and c-erbB-2 are used to treat colon and breast cancers. This study evaluated the significance and relationship of COX-2 and c-erbB-2 protein expression in untreated uterine cervical neoplasm. METHODS This study included 332 patients with uterine cervical neoplasm. We constructed tissue microarray blocks that included two cores from each donor tumor… CONTINUE READING

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