Cyclooxygenase-2, multidrug resistance 1, and breast cancer resistance protein gene polymorphisms and inflammatory bowel disease in the Danish population.

@article{stergaard2009Cyclooxygenase2MR,
  title={Cyclooxygenase-2, multidrug resistance 1, and breast cancer resistance protein gene polymorphisms and inflammatory bowel disease in the Danish population.},
  author={Mette Christina {\O}stergaard and Anja Ernst and Rodrigo Labouriau and Enrika Dagilien{\'e} and Henrik B Krarup and M. Keith. Christensen and Niels Thorsgaard and Bent Ascanius Jacobsen and Ulrik Tage-Jensen and Kim Overvad and Herman N Autrup and Vibeke Andersen},
  journal={Scandinavian journal of gastroenterology},
  year={2009},
  volume={44 1},
  pages={
          65-73
        }
}
OBJECTIVE Crohn's disease (CD) and ulcerative colitis (UC) are characterized by an impaired mucosal defence to normal constituents of the intestinal flora and a dysregulated inflammatory response. The purpose of the study was to investigate whether single nucleotide polymorphisms (SNPs) in genes involved in these processes were associated with CD and UC. MATERIAL AND METHODS Allele frequencies of the cyclooxygenase 2 (COX-2/PTGS2/PGHS2) G-765C and breast cancer resistance protein (BCRP/ABCG2… CONTINUE READING
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