Cyclohexa-2,5-diene-1,4-dione-based antiproliferative agents: design, synthesis, and cytotoxic evaluation

@inproceedings{Petronzi2013Cyclohexa25diene14dionebasedAA,
  title={Cyclohexa-2,5-diene-1,4-dione-based antiproliferative agents: design, synthesis, and cytotoxic evaluation},
  author={Carmen Petronzi and Michela Festa and Antonella Peduto and Mar{\'i}a Eugenia Castellano and Jessica Marinello and Ant{\'o}nio Massa and Anna Maria Capasso and Giovanni Capranico and Annalisa La Gatta and Mario de Rosa and Michele Caraglia and Rosanna Filosa},
  booktitle={Journal of experimental & clinical cancer research : CR},
  year={2013}
}
BackgroundTumors are diseases characterized by uncontrolled cell growth and, in spite of the progress of medicine over the years, continue to represent a major threat to the health, requiring new therapies. Several synthetic compounds, such as those derived from natural sources, have been identified as anticancer drugs; among these compounds quinone represent the second largest class of anticancer agents in use. Several studies have shown that these act on tumor cells through several mechanisms… CONTINUE READING
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References

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SHOWING 1-10 OF 32 REFERENCES

through mitochondrial damage stress and survivin downregulation

AA Gunatilaka, JM Berger, +5 authors DG Kingston
  • 2013

PinX1 regulation of telomerase activity and apoptosis in nasopharyngeal carcinoma cells

  • Journal of experimental & clinical cancer research : CR
  • 2012
VIEW 1 EXCERPT

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