Cyclodextrin-based siRNA delivery nanocarriers: a state-of-the-art review.

  title={Cyclodextrin-based siRNA delivery nanocarriers: a state-of-the-art review.},
  author={Kiran Chaturvedi and Kuntal Ganguly and Anandrao R. Kulkarni and Venkatarao H. Kulkarni and Mallikarjuna N. Nadagouda and Walter E. Rudzinski and Tejraj M. Aminabhavi},
  journal={Expert opinion on drug delivery},
  volume={8 11},
INTRODUCTION The discovery of synthetic small interfering RNA (siRNA) has led to a surge of interest in harnessing RNA interference (RNAi) technology for biomedical applications and drug development. Even though siRNA can be a powerful therapeutic drug, its delivery remains a major challenge, due to the difficulty in its cellular uptake. Naked siRNA has a… CONTINUE READING