Cyclodextrin-based polymeric materials: synthesis, properties, and pharmaceutical/biomedical applications.

@article{Manakker2009CyclodextrinbasedPM,
  title={Cyclodextrin-based polymeric materials: synthesis, properties, and pharmaceutical/biomedical applications.},
  author={Frank van de Manakker and Tina Vermonden and Cornelus F van Nostrum and Wim E Hennink},
  journal={Biomacromolecules},
  year={2009},
  volume={10 12},
  pages={3157-75}
}
This review describes the synthesis, properties, and, in particular, biomedical and pharmaceutical applications of an upcoming class of polymeric networks and assemblies based on cyclodextrins (CDs). CDs are cyclic oligosaccharides composed of alpha-1,4-coupled d-glucose units, which contain a hydrophobic internal cavity that can act as a host for various, generally lipophilic, guest molecules. Because of this unique physicochemical property, commonly referred to as inclusion complex formation… CONTINUE READING

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