Cyclo-oxygenase-2 inhibitors: when should they be used in the elderly?

  title={Cyclo-oxygenase-2 inhibitors: when should they be used in the elderly?},
  author={Ruth Lesley Savage},
  journal={Drugs & aging},
  volume={22 3},
Chronic pain in the elderly is frequently a result of arthritic disorders, particularly osteoarthritis. The cyclo-oxygenase (COX)-2 inhibitors are as effective as standard NSAIDs for the relief of pain and for improving function in elderly patients with osteoarthritis and rheumatoid arthritis. COX-2 inhibitors increase the risk of serious gastroduodenal adverse reactions but there is evidence that they carry a lower risk for these adverse effects than standard NSAIDs, except when there is… CONTINUE READING


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