Cyclo(Phe-Pro) modulates the expression of ompU in Vibrio spp.

  title={Cyclo(Phe-Pro) modulates the expression of ompU in Vibrio spp.},
  author={Dae-Kyun Park and Ko-Eun Lee and Chang-Ho Baek and In Hwang Kim and Ji-Hyoun Kwon and Won Koo Lee and K Z Lee and Byung-Soo Kim and Sang-Ho Choi and Kun-Soo Kim},
  journal={Journal of bacteriology},
  volume={188 6},
Vibrio vulnificus was found to produce a chemical that induced the expression of Vibrio fischeri lux genes. Electron spray ionization-mass spectrometry and 1H nuclear magnetic resonance analyses indicated that the compound was cyclo(L-Phe-L-Pro) (cFP). The compound was produced at a maximal level when cell cultures reached the onset of stationary phase. Sodium dodecyl sulfate-polyacrylamide gel analysis of the total proteins of V. vulnificus indicated that expression of OmpU was enhanced by… CONTINUE READING


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