CyclinD1, p53, E-cadherin, and VEGF discordant expression in paired regional metastatic lymph nodes of esophageal squamous cell carcinoma: a tissue array analysis.

@article{Luo2011CyclinD1PE,
  title={CyclinD1, p53, E-cadherin, and VEGF discordant expression in paired regional metastatic lymph nodes of esophageal squamous cell carcinoma: a tissue array analysis.},
  author={Kong-jia Luo and Yi Hu and Jing Wen and Jianhua Fu},
  journal={Journal of surgical oncology},
  year={2011},
  volume={104 3},
  pages={236-43}
}
BACKGROUND AND OBJECTIVES The correlation of biomarker expression between primary tumors and corresponding metastases has not yet been well reported in esophageal squamous cell carcinoma (ESCC). This study was to confirm whether primary ESCC tumors differ from their regional metastatic lymph nodes (RMLN) in CyclinD1, p53, E-cadherin, and vascular endothelial growth factor (VEGF) expression and determine prognostic value of their alteration. METHODS There were 134 patients with stage T3N1-3M0… CONTINUE READING