Cyclin L1 (CCNL1) gene alterations in human head and neck squamous cell carcinoma

@article{Muller2006CyclinL,
  title={Cyclin L1 (CCNL1) gene alterations in human head and neck squamous cell carcinoma},
  author={Dani{\`e}le Muller and R{\'e}gine Millon and Serge Theobald and Thomas Hussenet and Bohdan Wasylyk and Stanislas du Manoir and Joseph Abecassis},
  journal={British Journal of Cancer},
  year={2006},
  volume={94},
  pages={1041 - 1044}
}
We evaluated the expression and amplification of cyclin L1 (CCNL1) gene, a potential oncogene localised in the commonly amplified 3q25–28 region, in human head and neck squamous cell carcinomas (HNSCCs). Overexpression was observed in 55 out of 96 cases (57%) and amplification in nine out of 35 tumours (26%) with no relationships to the clinico-pathological… CONTINUE READING