Cyclin G1 is involved in G2/M arrest in response to DNA damage and in growth control after damage recovery

@article{Kimura2001CyclinGI,
  title={Cyclin G1 is involved in G2/M arrest in response to DNA damage and in growth control after damage recovery},
  author={Shinya H. Kimura and Masahito Ikawa and Akihiko Ito and Masaru Okabe and Hiroshi Nojima},
  journal={Oncogene},
  year={2001},
  volume={20},
  pages={3290-3300}
}
Cyclin G1 is one of the target genes of the transcription factor p53, and is induced in a p53-dependent manner in response to DNA damage. Although cyclin G1 has been implicated in a range of biological phenomena, its precise function remains unclear. Here we present an analysis of the physiological role of cyclin G1 using mice homozygous for a targeted disruption of the cyclin G1 gene. In order to clarify the role of cyclin G1 in the p53 pathway, downstream events such as apoptosis, cell growth… CONTINUE READING
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References

Publications referenced by this paper.
Showing 1-7 of 7 references

Cell Mol

W. Deppert
Life Sci., 55, 12 ± 27. Jayaraman L and Prives C. (1999). Cell Mol. Life Sci., 55, • 1999

Biochem

N. Wake
Biophys. Res. Commun., • 1998

Exp

HU Smith ML. Kontny, R Bortnick, AJ. Fornace
Cell Res., 230, 61 ± 68. • 1997

J

M Mulheisen, JW Hell, AF. Wahl
Biol. • 1997

J

Wahl AF.
Biol. Chem., 271, 6050 ± 6061. Hunter T. (1991). Semin. Cell Biol., 2, 213 ± 222. Ikawa M, Wada I, Kominami K, Watanabe D, Toshimori K, • 1996

Nature, 377, 552 ± 557

Hannon GJ.
Choisy Rossi C, Reisdorf P and Yonish Rouach E. (1998). • 1995

Teratocarcinoma and Embryonic Stem

EJ Robertson
1102