Cyclin D2 is a moderately oscillating nucleoprotein required for G1 phase progression in specific cell types.

Abstract

To explore regulation and function of cyclin D2, a candidate cell cycle-regulatory proto-oncogene, we examined subcellular localisation, cell type- and cell cycle-dependent expression, and requirement of cyclin D2 protein for G1 progression, in a panel of 40 human normal and cancer cell types. Except for lymphoid cells and sarcoma cell lines, expression of… (More)

Topics

  • Presentations referencing similar topics