Cyclin D1 overexpression and prognosis in colorectal adenocarcinoma.

  title={Cyclin D1 overexpression and prognosis in colorectal adenocarcinoma.},
  author={Kensaku Maeda and Y. S. Chung and Seong Man Kang and Michio Ogawa and Naoyoshi Onoda and Yukio Nishiguchi and Takashi Ikehara and Bunzo Nakata and Masashi Okuno and M. Sowa},
  volume={55 2},
Recently, it has been reported that cyclin D1 plays a major role in oncogenesis in various cancers; however, there have been few studies on the association of cyclin D1 overexpression and prognosis of patients with malignant tumors. We evaluated the prognostic significance of cyclin D1 overexpression in colorectal adenocarcinoma. One hundred twenty-three specimens resected from patients with colorectal adenocarcinomas were investigated by staining with a monoclonal antibody against cyclin D1… CONTINUE READING