Cyclin D1-negative blastoid mantle cell lymphoma identified by SOX11 expression.

@article{Zeng2012CyclinDB,
  title={Cyclin D1-negative blastoid mantle cell lymphoma identified by SOX11 expression.},
  author={Weifen F Zeng and Kai Fu and Leticia Quintanilla-Fend and M. S. Lim and Sarah L Ondrejka and E D Hsi},
  journal={The American journal of surgical pathology},
  year={2012},
  volume={36 2},
  pages={214-9}
}
SOX11 expression has been recently shown to be useful in the diagnosis of mantle cell lymphoma (MCL), including cyclin D1-negative MCL with typical morphology. We evaluated SOX11 expression pattern in B-cell non-Hodgkin lymphoma (B-NHL) subtypes to confirm specificity and used it as a feature to identify the first reported cases of cyclin D1-negative blastoid MCL. SOX11 expression was evaluated by immunohistochemistry in 140 cases of mature B-NHL, including 4 cases of suspected blastoid MCL… CONTINUE READING
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Differential diagnosis of cyclin D2+ mantle cell lymphoma based on fluorescence in situ hybridization and quantitative real-time-PCR

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