Cyclin D1 expression in normal oligodendroglia and microglia cells: its use in the differential diagnosis of oligodendrogliomas.

Abstract

Cyclin D1 regulates G1-S progression. In many carcinomas it is overexpressed and it might even correlate with prognosis. However, the amplification of CCND1 contributes to the loss of cell cycle control only in a small fraction of malignant gliomas. Cyclin D1 can be immunohistochemically demonstrated by DCS-6 mAb. In astrocytic gliomas the fraction of tumor… (More)

Topics

Cite this paper

@article{Bosone2001CyclinDE, title={Cyclin D1 expression in normal oligodendroglia and microglia cells: its use in the differential diagnosis of oligodendrogliomas.}, author={Ivana Bosone and Paolo Cavalla and Loredana Chiad{\`o}-Piat and Nancie Vito and Doris Schiffer}, journal={Neuropathology : official journal of the Japanese Society of Neuropathology}, year={2001}, volume={21 3}, pages={155-61} }