Cyclin/proliferation cell nuclear antigen immunohistochemistry does not improve the prognostic power of Dukes' or Jass' classifications for colorectal cancer.

@article{Neoptolemos1995CyclinproliferationCN,
  title={Cyclin/proliferation cell nuclear antigen immunohistochemistry does not improve the prognostic power of Dukes' or Jass' classifications for colorectal cancer.},
  author={John P Neoptolemos and G. D. Oates and K. M. Newbold and A. W. Mayo Robson and Chris McConkey and James Powell},
  journal={The British journal of surgery},
  year={1995},
  volume={82 2},
  pages={
          184-7
        }
}
Immunohistochemistry of cyclin/proliferation cell nuclear antigen (PCNA) is an attractive alternative to tumour cell proliferation activity determined by flow cytometry which has been shown to be independently predictive of survival in patients with colorectal carcinoma and to enhance Dukes' classification. Dukes' and Jass' histopathological classifications were determined in 91 patients who had undergone curative resection for cancer of the colon (n = 51) or rectum (n = 40) and followed up for… CONTINUE READING

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  • 2002
VIEW 9 EXCERPTS
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  • Annals of internal medicine
  • 1999
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  • Clinical cancer research : an official journal of the American Association for Cancer Research
  • 2000
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