Cyclic tension promotes osteogenic differentiation in human periodontal ligament stem cells.

@article{Shen2014CyclicTP,
  title={Cyclic tension promotes osteogenic differentiation in human periodontal ligament stem cells.},
  author={Tao Shen and Lin Qiu and Huijun Chang and Yanchun Yang and Congxiang Jian and Jian Xiong and Jixiang Zhou and Shiwu Dong},
  journal={International journal of clinical and experimental pathology},
  year={2014},
  volume={7 11},
  pages={7872-80}
}
Orthodontic forces result in alveolar bone resorption and formation predominantly on the pressure and tension sides of the tooth roots, respectively. Human periodontal ligament stem cells (PDLSCs) have demonstrated the capacity to differentiate into osteoblasts, and they play important roles in maintaining homeostasis and regenerating periodontal tissues. However, little is known about how PDLSCs contribute to osteoblastogenesis during orthodontic tooth movement on the tension side. In this… CONTINUE READING
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