Cyclic stretch increases splicing noise rate in cultured human fibroblasts

Abstract

Mechanical forces are known to alter the expression of genes, but it has so far not been reported whether they may influence the fidelity of nucleus-based processes. One experimental approach permitting to address this question is the application of cyclic stretch to cultured human fibroblasts. As a marker for the precision of nucleus-based processes, the… (More)
DOI: 10.1186/1756-0500-4-470

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