Cyclic stretch and compression forces alter microRNA-29 expression of human periodontal ligament cells.

@article{Chen2015CyclicSA,
  title={Cyclic stretch and compression forces alter microRNA-29 expression of human periodontal ligament cells.},
  author={Yinghua Chen and Arshad Mohammed and Maysaa Oubaidin and Carla A Evans and Xiaofeng Zhou and Xianghong Luan and Thomas G. H. Diekwisch and Phimon Atsawasuwan},
  journal={Gene},
  year={2015},
  volume={566 1},
  pages={13-7}
}
MicroRNAs (miRs) play an important role in the development and remodeling of tissues through the regulation of large cohorts of extracellular matrix (ECM) genes. The purpose of the present study was to determine the response of miR-29 family expression to loading forces and their effects on ECM gene expression in periodontal ligament cells, the key effector cell population during orthodontic tooth movement. In a comparison between miRs from human periodontal ligament cells (PDLCs) and alveolar… CONTINUE READING
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