Cyclic platelet dysfunction in IgE-mediated allergy.

  title={Cyclic platelet dysfunction in IgE-mediated allergy.},
  author={Joseph S. Gallagher and I. Leonard Bernstein and C A Maccia and Greta Lee Splansky and Helen I Glueck},
  journal={The Journal of allergy and clinical immunology},
  volume={62 4},
Diminished platelet aggregation responses to one or more aggregating agents were found in 25 of 32 patients with nasal allergy studied at the peak of the allergy season. Abnormal in-season platelet aggregation induced by epinephrine and collagen was significantly improved when repeated out-of-season, while incomplete platelet aggregation induced by adenosine diphosphate (ADP) and thrombin was unchanged. Recombination of an in-season serum factor with autologous, out-of-season normally… CONTINUE READING


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