Cyclic oscillations of basal plasma glucose and insulin concentrations in human beings.

@article{Lang1979CyclicOO,
  title={Cyclic oscillations of basal plasma glucose and insulin concentrations in human beings.},
  author={Darryl A Lang and David R. Matthews and Julian Peto and Robert C. Turner},
  journal={The New England journal of medicine},
  year={1979},
  volume={301 19},
  pages={1023-7}
}
In a study of whether oscillations in plasma glucose and insulin occur in human beings, plasma samples were taken at one-minute intervals from 10 normal subjects for periods lasting between one and two hours. In five subjects the basal plasma insulin concentrations cycled regularly, with a mean period of 13 minutes and mean amplitude of 1.6 mU per liter (11.5 pmol per liter). A concurrent plasma glucose cycle was demonstrated, with a mean amplitude (after averaging to minimize random error) of… CONTINUE READING

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