Cyclic nucleotides concentrations in the canine heart with regional ischemia. The role of cyclic AMP in ventricular fibrillation and the effect of dibutyryl cyclic AMP.

@article{Ukai1984CyclicNC,
  title={Cyclic nucleotides concentrations in the canine heart with regional ischemia. The role of cyclic AMP in ventricular fibrillation and the effect of dibutyryl cyclic AMP.},
  author={Masanori Ukai and Kouichi Ogawa},
  journal={Japanese circulation journal},
  year={1984},
  volume={48 3},
  pages={247-52}
}
The effect of the left anterior descending (LAD) coronary artery ligation on myocardial cyclic nucleotides and the role of these nucleotides in the development of ventricular fibrillation (VF) were studied in 135 mongrel dogs by means of sequential punching biopsies from the left ventricle. VF occurred in 50% of the non-premedicated groups. Significant… CONTINUE READING