Cyclic distension of fibrin-based tissue constructs: evidence of adaptation during growth of engineered connective tissue.

Abstract

Tissue engineering provides a means to create functional living tissue replacements. Here, we examine the effects of 3 weeks of cyclic distension (CD) on fibrin-based tubular tissue constructs seeded with porcine valve interstitial cells. CD with circumferential strain amplitude ranging from 2.5% to 20% was applied to evaluate the effects of CD on fibrin… (More)
DOI: 10.1073/pnas.0711217105

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@article{Syedain2008CyclicDO, title={Cyclic distension of fibrin-based tissue constructs: evidence of adaptation during growth of engineered connective tissue.}, author={Zeeshan H Syedain and Justin Weinberg and Robert T. Tranquillo}, journal={Proceedings of the National Academy of Sciences of the United States of America}, year={2008}, volume={105 18}, pages={6537-42} }