Cyclic di-GMP-mediated repression of swarming motility by Pseudomonas aeruginosa PA14 requires the MotAB stator.

@article{Kuchma2015CyclicDR,
  title={Cyclic di-GMP-mediated repression of swarming motility by Pseudomonas aeruginosa PA14 requires the MotAB stator.},
  author={Sherry L. Kuchma and Nicolas J. Delalez and Laura M. Filkins and Elizabeth Snavely and Judith P. Armitage and George A O'Toole},
  journal={Journal of bacteriology},
  year={2015},
  volume={197 3},
  pages={420-30}
}
The second messenger cyclic diguanylate (c-di-GMP) plays a critical role in the regulation of motility. In Pseudomonas aeruginosa PA14, c-di-GMP inversely controls biofilm formation and surface swarming motility, with high levels of this dinucleotide signal stimulating biofilm formation and repressing swarming. P. aeruginosa encodes two stator complexes, MotAB and MotCD, that participate in the function of its single polar flagellum. Here we show that the repression of swarming motility… CONTINUE READING
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